191140
Sigma-Aldrich

7-AMINOCEPHALOSPORANIC AC ID, 98%

Empform:

C10H12N2O5S

Synonyms English:

7-ACA

Nacres: NA.22
Mdl No: MFCD00005177
Fw: 272.28
Pubchem Substance Id: 24851470
CAS Number: 957-68-6
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Properties

Properties
antibiotic activity spectrum Gram-positive bacteria
applications peptide synthesis
assay 98%
Description 7-AMINOCEPHALOSPORANIC AC ID, 98%
form powder
inchi 1S/C10H12N2O5S/c1-4(13)17-2-5-3-18-9-6(11)8(14)12(9)7(5)10(15)16/h69H2-311H21H3(H1516)/t6-9-/m1/s1
inchi key HSHGZXNAXBPPDL-HZGVNTEJSA-N
Import License Temp. Regu
Check Obsolete No
Temperature Control 10
Shipping Mode DAS
Business Unit Chemistry

Description

Application

7-Aminocephalosporanic acid (7-ACA) can be used as a starting material to synthesize:
  • Cefotaxime by acylation reaction with S-benzothiazol-2-yl(2-amino-4-thiazolyl)(methoxyimino)thioacetate (MAEM) in the presence of triethylamine.
  • Cefpodoxime proxetil, a third-generation antibiotic via cefotaxime intermediate.
  • Sodium 3′-substituted cephalosporanate sulfone derivatives as potential inhibitors of β-lactamase.

General description

Chemical structure: ß-lactam

SAFETY INFORMATION

Signal Word

Danger

P261 - P272 - P280 - P284 - P302 + P352 - P333 + P313

RIDADRRIDADR

WGK Germany

WGK 3

Flash Point (F)

Not applicable

Flash Point (C)

Not applicable

Target Organs

Risk Statement

Supplemental Hazard Statements

DOCUMENTATION

Certificate of Analysis View Sample COA
Certificate of Origin

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