194905
Sigma-Aldrich

12-CROWN-4 98%

Empform:

C8H16O4

Synonyms English:

1,4,7,10-Tetraoxacyclododecane

Nacres: NA.22
Mdl No: MFCD00005103
Fw: 176.21
Pubchem Substance Id: 24851661
CAS Number: 294-93-9
Grouped product items
SKU Pack Size Availability Price Quantity
Request a Bulk Order Check Availability

Properties

Properties
assay 98%
bp 61-70 
bromine number ?C/0.5 
brush size diam. × l mmHg (lit.)
depth 1.089 
depth × h × w g/mL 
depth × overall h at 25 
depth × width ?C (lit.)
Description 12-CROWN-4 98%
frame w × l liquid
inlet and outlet nptm × nptm 1S/C8H16O4/c1-2-10-5-6-12-8-7-11-4-3-9-1/h1-8H2
inlet and outlet size XQQZRZQVBFHBHL-UHFFFAOYSA-N
Import License Temp. Regu
Check Obsolete No
Temperature Control 1554
Shipping Mode DAS
Business Unit Chemistry

Description

Application

12-Crown-4 can be used as:
  • A promoter in the synthesis of poly(diethylsiloxane) (PDES) from monomer hexaethylcyclotrisiloxane using NaOH as a catalyst via anionic ring-opening polymerization.
  • As an additive in the preparation of triarylmethane derivatives by palladium-catalyzed cross coupling reaction of aryl bromides with diarylmethane derivatives.
  • A phase transfer catalyst in organic synthesis.

General description

12-Crown-4 is a crown ether generally used as a ligand in coordination chemistry. It is also known as lithium ionophore because of its strong chelating property specific to lithium cation.

SAFETY INFORMATION

Signal Word

Danger

P304 + P340 + P310

RIDADRRIDADR

WGK Germany

WGK 3

Flash Point (F)

235.4 °F - closed cup

Flash Point (C)

113 °C - closed cup

Target Organs

Risk Statement

Supplemental Hazard Statements

DOCUMENTATION

Certificate of Analysis View Sample COA
Certificate of Origin

TECHNICAL SERVICE

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.