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198005
Sigma-Aldrich

2-CHLORO-1-METHYLPYRIDINI UM IODIDE, 97%

Empform:

C6H7ClIN

Synonyms English:

Mukaiyama reagent

Nacres: NA.22
Mdl No: MFCD00011984
Fw: 255.48
Pubchem Substance Id: 24851856
CAS Number: 14338-32-0
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Properties

Properties
assay 97%
Description 2-CHLORO-1-METHYLPYRIDINI UM IODIDE, 97%
inchi 1S/C6H7ClN.HI/c1-8-5-3-2-4-6(8)7
inchi key /h2-5H1H3
indiff. to chromic acid 1H/q+1
inherent viscosity /p-1
inlet and outlet diam. ABFPKTQEQNICFT-UHFFFAOYSA-M
Import License Temp. Regu
Check Obsolete No
Temperature Control 1554
Shipping Mode DAS
Business Unit Chemistry

Description

Application

2-Chloro-1-methylpyridinium iodide (CMPI) can be used as:
  • A dehydrating agent for the conversion of various aldoximes to nitriles, and alcohols into alkyl thiocyanates.
  • A cross-linking agent to fabricate biodegradable cross-linked hyaluronic acid film and gelatin membranes for biomedical applications.
  • A condensing agent to synthesize various β-lactams from β-amino acids.

General description

2-Chloro-1-methylpyridinium iodide (Mukaiyama reagent), is a commonly used reagent in organic synthesis for the activation of the hydroxy group of alcohols and carboxylic acids. It is used to synthesize derivatives of esters, lactones, amides, lactams, and ketenes from the corresponding carboxylic acids. It is also used as an efficient coupling reagent in the synthesis of peptides because of its low toxicity, simple reaction conditions, and also less expensive than EDC.

SAFETY INFORMATION

Signal Word

RIDADRRIDADR

WGK Germany

WGK 3

Flash Point (F)

Not applicable

Flash Point (C)

Not applicable

Target Organs

Risk Statement

Supplemental Hazard Statements

DOCUMENTATION

Certificate of Analysis View Sample COA
Certificate of Origin

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