For use in biological diagnostic assays and IVDs only
Biochem/physiol Actions
ProClin™ products contain active substances like CMIT and MIT which inhibit the Krebs cycle at four different check points, the enzymes pyruvate dehydrogenase, α-ketoglutarate dehydrogenase, succinate dehydrogenase, and NADH dehydrogenase. The inhibition of Krebs cycle leads to effective broad-spectrum biocidal activity against bacteria, fungi, and yeast.
General description
ProClin™
Immunogen
preservatives are water-soluble preparations of biocides that are generally used to increase the shelf life of reagents. ProClin™
Legal Information
300 comprises of 3% of 5-chloro-2-methyl-4-isothiazolin-3-one (CMIT) and 2-methyl-4-isothiazloin-3-one (MIT) in a salt-free proprietary glycol containing an alkly carboxylate stabilizer. It has a recommended working pH range as 2.5 - 8.5.
Packaging
For additional technical details on ProClin, including key features and mechanism of action, please visit www.sigmaaldrich.com/proclin.
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